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Reversing Mees' Lines: Kidney Filtration The Raw Vegan Plant-Based Detoxification & Regeneration Workbook for Healing Patients. Volume 5
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We are reporting nail changes like beau's line or mees' line occurring in a same patient after chemotherapy for the first time from our part of the world. There are only two case reports, having both mees lines and beu’s lines had been previously reported in the literature till date [7,8].
Causes of hypoalbuminemia include kidney damage, liver failure, too little protein intake, and inability to properly absorb protein. The paper noted that once albumin levels return to normal, muehrcke's lines disappear.
Mees lines can be a sign of arsenic poisoning or another harmful toxin like carbon monoxide, heavy metal poison, and cardiac problems. Your thumbnails can develop either a vertical or horizontal ridges.
This refers to discolored lines that cross the width of your toenails. Mees’ lines can be a sign of arsenic poisoning, hodgkin’s disease, malaria, leprosy, carbon monoxide poisoning or other systemic problems.
Background and objectives: the existence and prevalence of cerebral salt wasting (csw) or the preferred term, renal salt wasting (rsw), and its differentiation from syndrome of inappropriate antidiuretic hormone (siadh) have been controversial. This controversy stems from overlapping clinical and laboratory findings and an inability to assess the volume status of these patients.
Some heavy metals, including arsenic, can cause mees’ lines (horizontal white bands on your fingernails). Many of these symptoms could also result from other conditions and diseases. It’s usually best to have a medical professional help determine the cause before assuming that heavy metals are at fault for any particular set of symptoms.
Muehrcke's nails or muehrcke's lines (apparent leukonychia striata) are changes in the they are also seen in patients with end-stage kidney disease on hemodialysis, hodgkin's disease, pellagra, and sickle cell anaemia.
Lp is the unit permeability (known as porosity or “hydraulic conductivity”) of the capillary wall, which in the kidney refers to the glomerular capillary; s is the surface area available for fluid movement; pcap and pif are the capillary and interstitial fluid hydraulic pressures; πcap and πif are the capillary and interstitial fluid oncotic pressures; and s represents the reflection.
Mees' lines are a change that occurs in the color of the nail with no palpable ridges, typically described as white bands traversing the nail bed, running parallel to the lunula across the entire nail bed of the individual. This finding is indicative of arsenic [5], thallium [6], or other heavy metal poisoning.
Mees’ lines, are prominent horizontal marks that can appear on a person’s fingernails when they’ve died due to toxic heavy metal poisoning. It is often listed that renal failure (kidney failure) has occurred when mees’ lines are present on a body after death, particularly, acute kidney failure giving a person the appearance of ‘shock.
External examination should include examination for patchy alopecia as seen in chronic arsenic poisoning, mees’ line seen in nails in heavy metal poisoning, skin pigmentation in heavy metal poisoning, icterus indicates hepatotoxic poisons and also a sign of multi organ failure when the patient had been hospitalized for long duration.
Also, beau’s lines can indicate uncontrolled diabetes, psoriasis, severe zinc deficiency, and circulatory disease. Furthermore, mees’ lines are another type of horizontal nail ridges which can occur due to hodgkin’s disease, arsenic poisoning, leprosy, carbon monoxide poisoning, or malaria.
Arsenic initially accumulates in the liver, spleen, kidney, lungs, and gastrointestinal tract. A reversible bone marrow depression with pancytopenia may in episodes of multiple acute exposures, several mees lines may occur within.
Dec 15, 2017 mucocutaneous manifestations are well described in chronic kidney mees lines appear as a single, transverse, narrow whitish band on multiple nail plates.
Dec 1, 2009 chronic kidney disease (ckd) and esrd, treated with conventional hemo- or and reversal of lvh and cardiac fibrosis as a high priority is needed.
Absent kidney fanconi anemia extremities absent thumbs fanconi anemia thenar eminence hypoplasia; triphalangeal thumb diamond–blackfan syndrome spoon nails iron deficiency beau line (nails) heavy metal intoxication, severe illness mees line (nails) heavy metals, severe illness, sickle cell anemia dystrophic nails.
White nail bands like mees’ lines also appear with some infectious diseases, especially those accompanied by a high fever. These include illnesses as diverse as malaria, measles, leprosy, herpes zoster, and acute respiratory infections. In this condition, an individual’s nails may be part white and part brown.
Blood pressure, renal hemodynamics, electrolyte, and water excretion all display diurnal oscillation. Disturbance of these patterns is associated with hypertension and chronic kidney disease. Kidney oxygenation is dependent on oxygen delivery and consumption that in turn are determined by renal hemodynamics and metabolism. We hypothesized that kidney oxygenation also demonstrates 24-h.
In patients with mees’ lines, the nail bed is normal, but the nail itself is microscopically fragmented, probably because of the disruption of normal growth at the nail matrix during the insult.
Although thiazides and thiazide-like drugs are typically viewed as more effective than loop diuretics to treat hypertension in individuals with normal kidney function, as gfr declines, this relationship may reverse. This belief has both theoretical and observational underpinnings.
In episodes of multiple acute exposures, several mees lines may occur within a single nail. In some cases, the distance of the lines from the nail bed may be used to roughly gauge the date of the poisoning episode. Respiratory tract irritation (cough, laryngitis, mild bronchitis, and dyspnea) may result from acute exposure to airborne arsenic dust.
Mees lines also called “true leukonychia”, leukonychia striata or transverse leukonychia, are a change that occurs in the color of the nail with no palpable ridges, typically described as transverse non-blanching white bands that may extend the complete width of the nail plate, running parallel to the lunula across the entire nail bed of the individual that frequently affect.
Jan 26, 2009 beau's lines in the same nail indicate repeat drug. Definitions of the condition is reversible and often regresses spontaneously following drug therapy with cetiximab for renal cell carcinoma.
Another type of horizontal line is known as mees’ lines, which are horizontal discolorations that may be due to arsenic poisoning, hodgkin’s disease, malaria, leprosy, or carbon monoxide poisoning. Vertical ridges vertical ridges are typically a normal sign of aging and are not a cause for concern.
Thedre may also be chances of an acute kidney disease playing a part more so if there are visible beau’s lines on the nails. Moreover, if beau’s lines appear on all the nails of the fingers and toes then it is a sign of a more threatening condition like diabetes, thyroid disease, syphilis, or mumps.
Dorhout mees ej, ozbash c, akcicek f: cardiovascular disturbances in hemodialysis patients: the importance of volume overload. Koomans ha, geers ab, mees ej: plasma volume recovery after ultrafiltration in patients with chronic renal failure.
Mees lines: ( mēs ), horizontal white bands of the nails seen in chronic arsenical poisoning, and occasionally in leprosy.
Mees' lines appear after an episode of poisoning with arsenic, thallium or other heavy metals or selenium, and can also appear if the subject is suffering from kidney failure.
Mees' lines transverse while lines (usually one per nail, no depressions) that often can will disappear if pressure is placed over the line. It is strongly associated with arsenic poisoning, thallium poisoning and to a lesser extent other heavy metal poisoning.
Aii, demography of wt and adam15 knockout mice showing the frequency of abdominal aortic aneurysm formation and rupture in each genotype. B, ultrasound images of the abdominal aorta (lumen is indicated in yellow line, k indicates kidney) in each genotype.
Nov 24, 2016 - exam of the hand and nails can help diagnose liver disease (terry's nails), kidney disease (lindsay's nails), lung disease (nail clubbing), endocarditis, others.
Paraesthesia of hands and feet, mees lines in nails and rain drop pigmentation in hands are features of arsenic poisoning. Most reliable method of estimating blood alcohol level is gas liquid chromatography. After drinking liquor from local shop man develops confusion, vomiting and blurring of vision.
Sodium retention and edema are common features of nephrotic syndrome that are classically attributed to hypovolemia and activation of the renin–angiotensin–aldosterone system. However, numbers of clinical and experimental findings argue against this underfill theory. In this review we analyze data from the literature in both nephrotic patients and experimental models of nephrotic syndrome.
White transverse lines of the nails (mees lines) may occur with chemotherapy, acute arsenic intoxication, malignant tumors, myocardial infarction, thallium and antimony intoxication, fluorosis, and even during etretinate therapy. These lines are not due to changes in the nail bed, but are a true leukonychia, and the nails can grow out normally.
Any acute illness can produce transverse white lines, also known as mees lines. [11] in addition, they may be caused by heavy metal toxicity (classically associated with arsenic poisoning), chemotherapy, carbon monoxide poisoning, hodgkin disease, malaria, or leprosy.
Skin problems include transverse white bands on the fingernails (mees’ lines) and excessive accumulation of fluid in the soft layers of tissue below the skin (edema). Gastrointestinal symptoms include a flu-like illness (gastroenteritis) that is characterized by vomiting; abdominal pain; fever; and diarrhea, which, in some cases, may be bloody.
If you have this symptom, your doctor will take hair or tissue samples to check for arsenic in your body.
A series of thin bands (called mees’ lines) reveals arsenic poisoning. 6-9 nail thinning and fragility may present as lamellar onychoschizia, in which the nail’s upper layers detach, or as elkonyxis, in which the nail loses substance and becomes soft or pitted.
The indentations can appear when growth at the area under the cuticle is interrupted by injury or severe illness. Conditions associated with beau's lines include uncontrolled diabetes and peripheral vascular disease, as well as illnesses associated with a high fever, such as scarlet fever.
Mees line in heavy metal poisoning; skin pigmentation heavy metal poisoning; icterus hepatotoxic poisons; any details regarding injuries should be well documented, including; burns (chemical burns) puncture marks over the skin (in case of puncture marks on skin, surrounding 2cm of skin should be excised and sent to forensic science lab).
Mees’ lines, also known as aldrich–mees’ or reynolds lines, 2, 3 are 1- to 2-mm wide, transverse bands of leukonychia which run parallel to the lunula and usually affect all finger- and toenails.
Mees’ line is a single, thick white line running across the nail like a belt. It is associated with arsenic poisoning, thallium and other heavy-metal poisoning.
Beau line: nonpigmented transverse line or grooves in nail due to transient arrest of nail growth. This appears at the same time, on all the nails, a few weeks after an acute illness. This appears at the same time, on all the nails, a few weeks after an acute illness.
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Share on pinterest one or more horizontal white lines across the nail is known as striate or transverse leukonychia, also known as mees lines.
Shiga toxins (stxs) are expressed by the enteric pathogens shigella dysenteriae serotype 1 and certain serotypes of escherichia coli. Stx-producing bacteria cause bloody diarrhea with the potential to progress to acute renal failure. Stxs are potent protein synthesis inhibitors and are the primary virulence factors responsible for renal damage that may follow diarrheal disease.
Mees lines are not diagnostic of anything in particular eczema and psoriasis are skin-related autoimmune diseases, and both can produce these manifestations in the nails. Frankly, i had not heard of them being associated with cancer.
Transverse white “aldrich-mees” line on nails peripheral neuritis with itching, tingling and paresthesia of extremities with painful swelling (erythromelalgia) increased risk of cancer: bladder, kidney, liver, lung.
Enzymes that help reverse uv damage, and people who lack the genes for these enzymes suffer high rates beau's lines across the nail are associated with many serious conditions.
Mees' lines were originally described as being an indicator of arsenic intoxication; however we now know that many systemic diseases and medications can be the cause of mees' lines. Patients with true leukonychias that involve the entire width of the nail of several fingers warrant a thorough physical examination, medications review, and query.
Another white line, which grows out with the nail, is known as mees’ line. This is most commonly associated with arsenic or thallium poisoning, as noted in foot files. If these appear, then beware of any potential poisoners in your midst.
Since the kidney is a complex organ involving numerous specialized cell types performing highly regulated homeostatic functions these disorders often affect vital processes including water and electrolyte balance, blood pressure regulation, acid-base homeostasis, tissue oxygen supply, hormone and vitamin metabolism, growth and puberty, innate.
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